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There is still confusion about the laws regarding CBD, how to use it, and its safety and effectiveness. CBD products are legal, though their legal status varies among states. The Food and Drug Administration (FDA) does not control most CBD products and as a result, the recommended amount of CBD per dose can vary dramatically from brand to brand.
This article includes information about the recommended dosages of CBD, backed by the research on what dosages are safe and effective. The article also touches on the health benefits of CBD as well as the possible risks of using CBD products.
To date, the FDA has only approved one cannabis-derived product, which is called Epidiole, While Epidole helps with the treatment of seizures in people with severe types of epilepsy called Lennox-Gastaut syndrome and Dravet syndrome, it is only available by prescription.
The dosage for Epidiolex, a form of CBD oil, is as follows:
- The starting dosage is 2.5 milligrams per kilogram of body weight (mg/kg) twice daily, making a total dosage of 5 mg/kg each day.
- After 1 week, people may increase the dosage to 5 mg/kg twice daily, which is a total of 10 mg/kg per day.
All other products that contain CBD fall outside FDA regulations, so there are no official guidelines for their dosage. Before using any other CBD products, one should consult their doctor about appropriate dosages.
The dosage that a person takes will depend on the method of administration that they are using and the specific product. Methods of administration include:
- CBD oil solutions
- CBD capsules
- tablets that a person places under the tongue (sublingual)
- nasal sprays
Recently, a wider range of products containing CBD has become available. These items include food products, dietary supplements, cosmetics, and animal health products.
Research into CBD therapy is still in its early days, and scientists need to conduct many more research studies to determine the benefits and risks of CBD products. Importantly, researchers need to work out the ideal CBD dosages that are both safe and effective for each condition.
As a therapy, CBD oil has gained a high level of research interest. At Medical News Today, we have covered what the research to date has shown about the role of CBD in the following conditions:
- weight loss
- attention deficit hyperactivity disorder (ADHD)
According to a World Health Organization (WHO) report, research has suggested that CBD oil may also have therapeutic benefits for the following conditions:
- Alzheimer's disease
- Parkinson's disease
- multiple sclerosis
- Huntington's disease
- hypoxia-ischemia injury
- inflammatory diseases
- rheumatoid arthritis
- inflammatory bowel disease
- cardiovascular disease
- diabetic complications
In clinical studies, researchers have used various oral dosages of CBD, ranging from 100–800 mg per day, some studies use even higher dosages. Some individuals have reported improvement in psychosis after taking 1,200 mg per day for a few weeks. In another study, people with schizophrenia reported benefits after taking dosages of 40–1,280 mg per day for 4 weeks.
In a study into the effects of CBD in people with Parkinson's disease and psychosis, six participants showed significant improvement in symptoms with a dosage of 150 mg per day of CBD.
The following table lists the method of administration and dosage of CBD that researchers have used to study its therapeutic effects on different medical conditions.
|Medical condition||Dose of CBD||Form|
|bowel disease||5 mg twice daily||sublingual (olive oil drops)|
|type 2 diabetes||100 mg twice daily||oral|
|pain due to cancer||50–600 mg per day||oral|
|Parkinson's disease||75–300 mg per day||oral|
|Huntington's disease||Up to 12 sprays per day||Sativex nasal spray (contains CBD and THC in 1:1 concentration)|
To find out whether a CBD product is safe for you and to determine the effective dosage, one should consult a doctor first.